Semax and NAD+ Nasal Spray: Advanced Neurocognitive and Metabolic Support for Prescribers
As prescribers increasingly address cognitive performance, neurologic resilience, and metabolic health, therapies that support both brain function and cellular energy are gaining traction. Semax and NAD+ nasal spray represent two complementary compounded options that allow clinicians to target neurocognitive pathways and mitochondrial health through a patient-friendly delivery system.
Semax: Targeted Neurocognitive Support
Semax is a synthetic peptide derived from adrenocorticotropic hormone (ACTH) fragments and is commonly utilized for its neuroprotective and nootropic properties. Clinically, Semax has been associated with improved focus, memory, stress resilience, and cognitive endurance. It works by modulating brain-derived neurotrophic factor (BDNF), supporting synaptic plasticity and neuronal signaling.
For prescribers, Semax offers a non-stimulant option for patients experiencing brain fog, cognitive fatigue, stress-related decline, or performance demands. Delivered via nasal spray, Semax bypasses first-pass metabolism and allows for direct access to central nervous system pathways, improving consistency and patient adherence.
NAD+ Nasal Spray: Cellular Energy and Brain Metabolism
NAD+ plays a critical role in mitochondrial energy production, DNA repair, and cellular resilience. Declining NAD+ levels are associated with fatigue, impaired cognition, and metabolic slowdown. NAD+ nasal spray provides a non-invasive alternative to injectable or IV NAD+ therapies, offering prescribers a practical option for patients seeking sustained cellular support.
From a clinical standpoint, NAD+ nasal delivery supports mitochondrial function while avoiding barriers associated with infusion-based therapy. This can be particularly valuable for patients requiring ongoing cognitive and metabolic support.
Why Combine Semax and NAD+ Nasal Spray
While Semax primarily supports neurologic signaling and cognitive performance, NAD+ addresses cellular energy and metabolic efficiency. Used together, they allow prescribers to support both upstream energy production and downstream cognitive output. This combination may be appropriate for patients with cognitive fatigue, burnout, neuro-metabolic stress, or age-related cognitive decline.
Restore’s Role as a Compounding Partner
At Restore Compounding Pharmacy, we work directly with prescribers to compound Semax and NAD+ nasal spray formulations with precision, consistency, and clinical intent. Our pharmacists understand stability, dosing strategies, and patient tolerability considerations, and we prioritize communication and turnaround times to support busy practices.
For clinicians seeking a reliable, customer-service–driven compounding pharmacy with experience in advanced neurocognitive therapies, Restore provides the clinical partnership necessary to integrate Semax and NAD+ nasal spray confidently into patient care plans.
